I guess it's personal preference. Glock are absolutely reliable, so I get that part. I guess I just don't love the way they shoot (the ones I have shot at least). When it comes to handguns 1911's have always been the most comfortable to me, mostly. My favorites I've owned are Sig, Kimber, and FN. I shot a Les Baer that was ridiculous too. Just haven't ever been much of a Glock guy, but I have friends that swear by them.
I'm also 6'3" with bigish hands so finding something that fits comfortably in my hands isn't always easy.