Maybe
@TheOriginalCane remembers. We could definitely do a list.
2021:
Marco Wilson - 4th round - as a rookie, 13 starts, 2 passed defensed
Shawn Davis - 5th round - as a rookie, he was waived from the team that drafted him, and released from the practice squad; he signed to another practice squad and played in one game in December
2020:
CJ Henderson - 1st round - #9 overall pick, given a 4-year fully-guaranteed contract, traded away a year later for a 5th round pick and a 3rd round pick
2019:
CJ Gardner-Johnson - 4th round - sucker-punched by multiple teammates AND opponents
2018:
Duke Dawson - 2nd round - did not appear in a single game for the team who drafted him, and was traded one year later for a 6th round pick; out of football; total career interceptions - zero-point-zero
Marcell Harris - 6th round - biggest play of rookie season was a late hit on Mitchell Trubisky; waived after a year; has caught on with the 49ers, but has been converted to linebacker
2017:
Marcus Maye - 2nd round - did OK for the J-E-T-S-Jets-Jets-Jets, but several injuries; did make it to a second contract, but with the Saints
Quincy Wilson - 2nd round - even though a starting spot opened up when PBJ P-Rob left in free agency, coaching great Chuck Pagano put the rook at 3rd on the depth chart, and later healthy-scratched Wilson multiple times; after three years, traded to the J-E-T-S for the last (non-comp) pick of the 6th round, and was waived in-season; practice squad player for the Giants; reserve/future contract with the Phins
Teeeezzzz Tabor - 2nd round - cut by the team that drafted him after 2 years; practice squad ever since
2016:
Vernon Hargreaves - 1st round - even though the team that drafted him exercised the 5th year option, he was cut mid-season in his 4th year; has not done much with two successive teams; most famous play is running onto the field during Super Bowl LVI, despite being in active for the game
Keanu Neal - 1st round - in fairness, he made one Pro Bowl and got a 5th year rookie contract extension; he then had season-ending injuries in back-to-back seasons; got to a (one-year) second contract with a new team, and was switched to linebacker; highlight of his career was ending the career of fellow Gaytor Jordan Reed on a helmet-to-helmet hit
2014:
Jaylen Watkins - 4th round - released by the team that drafted him after one year; largely practice squad since
2013:
Matt Elam - 1st round - decent first year, terrible thereafter, drafting team did not pick up his 5th year and let him waslk after he was arrested; has played in Canada, XFL, and the IFL since then
Josh Evans - 6th round - played 3 seasons for the team that drafted him, cut before 4th season; last played in the AAF
2011:
Ahmad Black - 5th round - cut midway through his third season with the team that drafted him, did not play again