There aren’t really defenses designed to stop “tempo.” You can stop the play, and that’s great. But that’s not you stopping “tempo.”
Even if such a thing exists (and it doesn’t), another argument behind tempo is to run as many plays as you can because the more plays run in a game, the more it favors the better team. The larger the sample size, the more the cream is going to rise to the top. The more you slow the game down, the more lesser teams have a chance to win. This is why the military academies eat up the play clock.